P39T (p.Pro39Thr) variant of RNF215 (RING finger protein 215)
P39T (p.Pro39Thr) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P39T (p.Pro39Thr) variant details
- p.Pro39Thr
- 1000Genomes rs1205469977
- TOPMed rs1205469977
- gnomAD rs1205469977
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 24.00
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the 1KG:PUR population (allele frequency 0.0051)
- Structural context available