P28R (p.Pro28Arg) variant of RNF215 (RING finger protein 215)
P28R (p.Pro28Arg) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P28R (p.Pro28Arg) variant details
- p.Pro28Arg
- gnomAD rs1569200277
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.74
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the HGDP:BANTUKENYA population (allele frequency 0.15)
- Structural context available