P18S (p.Pro18Ser) variant of RNF215 (RING finger protein 215)
P18S (p.Pro18Ser) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- TOPMed rs1259351350
- gnomAD rs1259351350
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.30
- ESM-1b 0.00
- AlphaMissense 0.08
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available