P16S (p.Pro16Ser) variant of RNF215 (RING finger protein 215)
P16S (p.Pro16Ser) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
P16S (p.Pro16Ser) variant details
- p.Pro16Ser
- TOPMed rs1933617074
- gnomAD rs1933617074
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.31
- ESM-1b 0.04
- AlphaMissense 0.10
- CADD 23.50
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the HGDP:CAMBODIAN population (allele frequency 0.1)
- Structural context available