P15S (p.Pro15Ser) variant of RNF215 (RING finger protein 215)
P15S (p.Pro15Ser) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- Ensembl rs1440040257
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.25
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 23.40
- PolyPhen-2 0.86
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available