L9P (p.Leu9Pro) variant of RNF215 (RING finger protein 215)
L9P (p.Leu9Pro) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- gnomAD rs1428948535
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.05
- CADD 21.30
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the HGDP:CAMBODIAN population (allele frequency 0.1)
- Structural context available