G51W (p.Gly51Trp) variant of RNF215 (RING finger protein 215)
G51W (p.Gly51Trp) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G51W (p.Gly51Trp) variant details
- p.Gly51Trp
- Ensembl rs1933614193
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.07
- ESM-1b 0.25
- AlphaMissense 0.26
- CADD 19.50
- PolyPhen-2 0.42
- SIFT 0.01
- Most common in the HGDP:RUSSIAN population (allele frequency 0.08)
- Structural context available