G45R (p.Gly45Arg) variant of RNF215 (RING finger protein 215)
G45R (p.Gly45Arg) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G45R (p.Gly45Arg) variant details
- p.Gly45Arg
- gnomAD rs1933614653
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.22
- CADD 23.20
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the HGDP:PATHAN population (allele frequency 0.083)
- Structural context available