A37V (p.Ala37Val) variant of RNF215 (RING finger protein 215)
A37V (p.Ala37Val) in RNF215 (RING finger protein 215) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A37V (p.Ala37Val) variant details
- p.Ala37Val
- gnomAD rs1471190139
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.03
- ESM-1b 0.00
- AlphaMissense 0.18
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available