P8S (p.Pro8Ser) variant of RNF207 (RING finger protein 207)
P8S (p.Pro8Ser) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P8S (p.Pro8Ser) variant details
- p.Pro8Ser
- TOPMed rs910748567
- gnomAD rs910748567
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.01
- CADD 12.90
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available