P35T (p.Pro35Thr) variant of RNF207 (RING finger protein 207)
P35T (p.Pro35Thr) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
P35T (p.Pro35Thr) variant details
- p.Pro35Thr
- gnomAD 1-6206638-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.785
- REVEL 0.90
- CADD 26.70
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available