P26L (p.Pro26Leu) variant of RNF207 (RING finger protein 207)
P26L (p.Pro26Leu) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P26L (p.Pro26Leu) variant details
- p.Pro26Leu
- ExAC rs775187088
- TOPMed rs775187088
- gnomAD rs775187088
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.25
- CADD 21.20
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available