P22L (p.Pro22Leu) variant of RNF207 (RING finger protein 207)
P22L (p.Pro22Leu) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
P22L (p.Pro22Leu) variant details
- p.Pro22Leu
- gnomAD rs1667912066
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.55
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available