P22A (p.Pro22Ala) variant of RNF207 (RING finger protein 207)
P22A (p.Pro22Ala) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
P22A (p.Pro22Ala) variant details
- p.Pro22Ala
- gnomAD rs1361903684
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.60
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available