L37P (p.Leu37Pro) variant of RNF207 (RING finger protein 207)
L37P (p.Leu37Pro) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
L37P (p.Leu37Pro) variant details
- p.Leu37Pro
- ExAC rs748183755
- gnomAD rs748183755
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.90
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available