H21Y (p.His21Tyr) variant of RNF207 (RING finger protein 207)
H21Y (p.His21Tyr) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
H21Y (p.His21Tyr) variant details
- p.His21Tyr
- gnomAD 1-6206596-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.23
- CADD 24.50
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available