G47D (p.Gly47Asp) variant of RNF207 (RING finger protein 207)
G47D (p.Gly47Asp) in RNF207 (RING finger protein 207) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G47D (p.Gly47Asp) variant details
- p.Gly47Asp
- NCI-TCGA Cosmic COSV6500
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.39
- CADD 19.90
- PolyPhen-2 0.44
- SIFT 0.45
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available