E33K (p.Glu33Lys) variant of RNF207 (RING finger protein 207)
E33K (p.Glu33Lys) in RNF207 (RING finger protein 207) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- NCI-TCGA Cosmic COSV6500
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.32
- CADD 23.60
- PolyPhen-2 0.73
- SIFT 0.15
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available