D16Y (p.Asp16Tyr) variant of RNF207 (RING finger protein 207)
D16Y (p.Asp16Tyr) in RNF207 (RING finger protein 207) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D16Y (p.Asp16Tyr) variant details
- p.Asp16Tyr
- TOPMed rs1184064725
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.31
- CADD 27.10
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available