V84A (p.Val84Ala) variant of RHEB (GTP-binding protein Rheb)
V84A (p.Val84Ala) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
V84A (p.Val84Ala) variant details
- p.Val84Ala
- Ensembl rs776865999
- Missense
- Variant Prioritization Score for Impact Estimate 0.8
- REVEL 0.88
- MetaLR 0.81
- MetaSVM 0.82
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available