T73I (p.Thr73Ile) variant of RHEB (GTP-binding protein Rheb)
T73I (p.Thr73Ile) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
T73I (p.Thr73Ile) variant details
- p.Thr73Ile
- gnomAD 7-151477390-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.62
- MetaLR 0.31
- MetaSVM -0.46
- CADD 24.60
- PolyPhen-2 0.28
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available