S86Y (p.Ser86Tyr) variant of RHEB (GTP-binding protein Rheb)
S86Y (p.Ser86Tyr) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.88 / 1. The record also includes population frequency data, published literature, and structural context.
S86Y (p.Ser86Tyr) variant details
- p.Ser86Tyr
- gnomAD 7-151477351-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.881
- REVEL 0.93
- MetaLR 0.79
- MetaSVM 0.87
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available