S68Y (p.Ser68Tyr) variant of RHEB (GTP-binding protein Rheb)
S68Y (p.Ser68Tyr) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data, published literature, and structural context.
S68Y (p.Ser68Tyr) variant details
- p.Ser68Tyr
- gnomAD 7-151477405-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.802
- REVEL 0.84
- MetaLR 0.64
- MetaSVM 0.42
- CADD 29.60
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available