S68P (p.Ser68Pro) variant of RHEB (GTP-binding protein Rheb)
S68P (p.Ser68Pro) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
S68P (p.Ser68Pro) variant details
- p.Ser68Pro
- gnomAD 7-151477406-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.726
- REVEL 0.83
- MetaLR 0.55
- MetaSVM 0.18
- CADD 29.20
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available