I82T (p.Ile82Thr) variant of RHEB (GTP-binding protein Rheb)
I82T (p.Ile82Thr) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
I82T (p.Ile82Thr) variant details
- p.Ile82Thr
- gnomAD 7-151477363-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.815
- REVEL 0.93
- MetaLR 0.77
- MetaSVM 0.76
- CADD 27.10
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available