I76T (p.Ile76Thr) variant of RHEB (GTP-binding protein Rheb)
I76T (p.Ile76Thr) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
I76T (p.Ile76Thr) variant details
- p.Ile76Thr
- gnomAD 7-151477381-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.515
- REVEL 0.51
- MetaLR 0.33
- MetaSVM -0.57
- CADD 23.90
- PolyPhen-2 0.04
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available