I76M (p.Ile76Met) variant of RHEB (GTP-binding protein Rheb)
I76M (p.Ile76Met) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
I76M (p.Ile76Met) variant details
- p.Ile76Met
- gnomAD 7-151477380-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.25
- MetaLR 0.39
- MetaSVM -0.49
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.61
- Population evidence available
- Structural context available
- Literature evidence available