I69T (p.Ile69Thr) variant of RHEB (GTP-binding protein Rheb)
I69T (p.Ile69Thr) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
I69T (p.Ile69Thr) variant details
- p.Ile69Thr
- gnomAD 7-151477402-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.618
- REVEL 0.68
- MetaLR 0.30
- MetaSVM -0.27
- CADD 27.90
- PolyPhen-2 0.96
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available