G118W (p.Gly118Trp) variant of RHEB (GTP-binding protein Rheb)
G118W (p.Gly118Trp) in RHEB (GTP-binding protein Rheb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data, published literature, and structural context.
G118W (p.Gly118Trp) variant details
- p.Gly118Trp
- gnomAD 7-151471422-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.889
- REVEL 0.93
- MetaLR 0.87
- MetaSVM 1.04
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available