V25M (p.Val25Met) variant of RET (P07949)
V25M (p.Val25Met) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
V25M (p.Val25Met) variant details
- p.Val25Met
- gnomAD 10-43077331-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.23
- MetaLR 0.36
- MetaSVM -0.58
- CADD 25.50
- PolyPhen-2 0.14
- SIFT 0.32
- Population evidence available
- Structural context available
- Literature evidence available