T5S (p.Thr5Ser) variant of RET (P07949)
T5S (p.Thr5Ser) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
T5S (p.Thr5Ser) variant details
- p.Thr5Ser
- gnomAD 10-43077271-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.17
- MetaLR 0.81
- MetaSVM 0.16
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.77
- Population evidence available
- Structural context available
- Literature evidence available