L16P (p.Leu16Pro) variant of RET (P07949)
L16P (p.Leu16Pro) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
L16P (p.Leu16Pro) variant details
- p.Leu16Pro
- gnomAD 10-43077305-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.61
- MetaLR 0.91
- MetaSVM 0.85
- CADD 23.80
- PolyPhen-2 0.14
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available