L13M (p.Leu13Met) variant of RET (P07949)
L13M (p.Leu13Met) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L13M (p.Leu13Met) variant details
- p.Leu13Met
- gnomAD 10-43077295-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.39
- MetaLR 0.91
- MetaSVM 0.73
- CADD 9.76
- PolyPhen-2 0.09
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available