L11R (p.Leu11Arg) variant of RET (P07949)
L11R (p.Leu11Arg) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
L11R (p.Leu11Arg) variant details
- p.Leu11Arg
- Ensembl rs2132498173
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- REVEL 0.53
- MetaLR 0.94
- MetaSVM 0.79
- CADD 23.60
- PolyPhen-2 0.68
- SIFT 0.36
- Population evidence available
- Structural context available