L11P (p.Leu11Pro) variant of RET (P07949)
L11P (p.Leu11Pro) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- gnomAD 10-43077290-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.60
- MetaLR 0.95
- MetaSVM 0.96
- CADD 24.00
- PolyPhen-2 0.68
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available