G7C (p.Gly7Cys) variant of RET (P07949)
G7C (p.Gly7Cys) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
G7C (p.Gly7Cys) variant details
- p.Gly7Cys
- gnomAD 10-43077277-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.48
- MetaLR 0.93
- MetaSVM 0.81
- CADD 22.40
- PolyPhen-2 0.51
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available