G23C (p.Gly23Cys) variant of RET (P07949)
G23C (p.Gly23Cys) in RET (P07949) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
G23C (p.Gly23Cys) variant details
- p.Gly23Cys
- gnomAD 10-43077325-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.42
- MetaLR 0.95
- MetaSVM 0.88
- CADD 23.70
- PolyPhen-2 0.83
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available