G10W (p.Gly10Trp) variant of RET (P07949)
G10W (p.Gly10Trp) in RET (P07949) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
G10W (p.Gly10Trp) variant details
- p.Gly10Trp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.52
- MetaLR 0.96
- MetaSVM 0.88
- CADD 29.70
- PolyPhen-2 1.00
- SIFT 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available