Y89S (p.Tyr89Ser) variant of REL (Proto-oncogene c-Rel)
Y89S (p.Tyr89Ser) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
Y89S (p.Tyr89Ser) variant details
- p.Tyr89Ser
- gnomAD 2-60894509-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.52
- MetaLR 0.29
- MetaSVM -0.54
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available