Y88S (p.Tyr88Ser) variant of REL (Proto-oncogene c-Rel)
Y88S (p.Tyr88Ser) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
Y88S (p.Tyr88Ser) variant details
- p.Tyr88Ser
- gnomAD 2-60894506-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.26
- MetaLR 0.23
- MetaSVM -0.73
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available