Y88C (p.Tyr88Cys) variant of REL (Proto-oncogene c-Rel)
Y88C (p.Tyr88Cys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
Y88C (p.Tyr88Cys) variant details
- p.Tyr88Cys
- rs918803156
- gnomAD 2-60894506-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.25
- MetaLR 0.22
- MetaSVM -0.74
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available