Y6C (p.Tyr6Cys) variant of REL (Proto-oncogene c-Rel)
Y6C (p.Tyr6Cys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
Y6C (p.Tyr6Cys) variant details
- p.Tyr6Cys
- gnomAD 2-60891689-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.07
- MetaLR 0.06
- MetaSVM -1.05
- CADD 16.80
- PolyPhen-2 0.39
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available