Y55C (p.Tyr55Cys) variant of REL (Proto-oncogene c-Rel)
Y55C (p.Tyr55Cys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Y55C (p.Tyr55Cys) variant details
- p.Tyr55Cys
- gnomAD 2-60894407-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.24
- MetaLR 0.16
- MetaSVM -0.86
- CADD 21.90
- PolyPhen-2 0.02
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available