V66L (p.Val66Leu) variant of REL (Proto-oncogene c-Rel)
V66L (p.Val66Leu) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
V66L (p.Val66Leu) variant details
- p.Val66Leu
- rs760737163
- gnomAD 2-60894439-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.48
- MetaLR 0.40
- MetaSVM -0.07
- CADD 24.30
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available