T67K (p.Thr67Lys) variant of REL (Proto-oncogene c-Rel)
T67K (p.Thr67Lys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data, published literature, and structural context.
T67K (p.Thr67Lys) variant details
- p.Thr67Lys
- gnomAD 2-60894443-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.708
- REVEL 0.75
- MetaLR 0.42
- MetaSVM 0.05
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available