T67A (p.Thr67Ala) variant of REL (Proto-oncogene c-Rel)
T67A (p.Thr67Ala) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
T67A (p.Thr67Ala) variant details
- p.Thr67Ala
- gnomAD 2-60894442-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.614
- REVEL 0.67
- MetaLR 0.37
- MetaSVM -0.14
- CADD 25.80
- PolyPhen-2 0.99
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available