T64K (p.Thr64Lys) variant of REL (Proto-oncogene c-Rel)
T64K (p.Thr64Lys) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
T64K (p.Thr64Lys) variant details
- p.Thr64Lys
- gnomAD 2-60894434-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.32
- MetaLR 0.26
- MetaSVM -0.58
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available