S3Y (p.Ser3Tyr) variant of REL (Proto-oncogene c-Rel)
S3Y (p.Ser3Tyr) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
S3Y (p.Ser3Tyr) variant details
- p.Ser3Tyr
- gnomAD 2-60881848-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -0.82
- CADD 25.00
- PolyPhen-2 0.14
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available