S3P (p.Ser3Pro) variant of REL (Proto-oncogene c-Rel)
S3P (p.Ser3Pro) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
S3P (p.Ser3Pro) variant details
- p.Ser3Pro
- gnomAD 2-60881847-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.16
- MetaLR 0.08
- MetaSVM -0.98
- CADD 24.20
- PolyPhen-2 0.07
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available