R85T (p.Arg85Thr) variant of REL (Proto-oncogene c-Rel)
R85T (p.Arg85Thr) in REL (Proto-oncogene c-Rel) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
R85T (p.Arg85Thr) variant details
- p.Arg85Thr
- gnomAD 2-60894497-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.15
- MetaLR 0.16
- MetaSVM -0.93
- CADD 23.80
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available